Como antiarrítmico: • Dosis inicial de carga: 1,25 mg/kg i.v en infusión intermitente, cada 5 min. hasta un total de 15mg/kg. • Mantenimiento. calculo de dosis factor goteo regla de tres. CONECTAR A EQUIPO MACRO IV DIRECTA FENITOINA (EPAMIN) ANTICONVULSIVANTE. DIFENILHIDANTOINA (Fenitoina) Mecanismo de Acción: . en el hígado y el 35 % de una dosis oral aparece en la orina, vida media 4 h.

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Selhorst JB, Kaukman B. Karyometric parameters average values difenilhidanyoina the epithelium thorny layer cells nucleus from anterior dorsal, posterior dorsal and ventral regions of tongue of control C and treated T fetuses.

Posteriormente a la suspension de la DFH y la exeresis del quiste temporal mejoro su cuadro convulsivo, aunque quedo con ataxia de miembros inferiores y asinergia de tronco, cuadro con el que fue dado de alta. Rapport 3 Estimated H-index: Neme 1 Estimated H-index: Consult with your healthcare professional before taking any medication.

The morphometric difenilhidanyoina were estimated using drawings 50 sketches made dkfenilhidantoina paper and then measured using a millimetric scale, obtained with the aid of a light camera JENA, with final magnification X.

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The present work demonstrated that the phenytoin treatment caused morphologic and morphometric alterations in the rats’ lingual mucosa. This means it is still under development and may contain inaccuracies.


Other Papers By First Author. Phenytoin – induced cleft palate: Ney 3 Estimated H-index: Little attention has been paid in the literature to the acute DFH intoxication bearing cerebellar symptoms.

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Dam 70 Estimated H-index: Se presenta un caso clinico desarrollado durante difeinlhidantoina tratamiento a largo plazo con fenitoina en una paciente epileptica. Longer periods of clampage minutes and higher phenytoin doses induce more serious malformations, as example: Behavioral outcome after prenatal exposure to phenytoin in rats.

The effects of phenytoin on rat development: Diphenylhydantoin teratogenicity in rats. Histological aspects of the epithelium of tongue’s anterior dorsal region of control group a and treated group b. Harald Masur 8 Estimated H-index: Casilla D Temuco – Chile Tel.: The results showed that the average body weight of treated animals decreased. For both cases, the malformations are preceded by the same precocious pathological changes edema, vascular breach, hemorrhage and at last tissue necrosis during the same pregnancy phase.


How to cite this article. Effect difenillhidantoina prenatal phenytoin administration on postnatal development of the rat: Teratogenic potential of almokalant, dofetilide, and d-sotalol: Michito Adachi 11 Estimated H-index: Parenchymatous cerebellar degeneration complicating diphenylhydantoin Dilontin therapy. In this work, Wistar female rats were employed in order to check the phenytoin action in the lingual epithelium as well as in the tongue muscles.


Cerebellar atrophy following acute intoxication with phenytoin.

The epithelium presented hypotrophied, which was demonstrated by histometric data statistically different from the respective control. TC and MRI did not show cerebellar atrophy. Arch Neurol Cerebellar degeneration with clinical manifestation in chronic epileptic patients. The posterior dorsal region of the tongue showed to be less thick, comparing to the anterior region, however, with cell sifenilhidantoina characteristics very similar to the anterior region and, also showed the absence of granular and horny layers Fig.

Resaltar la importancia y posibilidad de efectuar un diagnostico precoz. In the anterior dorsal region of the tongue, the epithelium showed to be less thick, with no papilla; the cells from the prickle-cell and basal layer showed to be more rounded and morphologically very alike, and their nuclei showed loose chromatin, evident nucleolus, and two-nucleolus nuclei were often observed.