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Discussion Normal individuals had more years of education in comparison to the other groups, a result previously identified in other studies 6.

File:Atlantic Express MCI 180.jpg

Categorical “golden standard” diagnoses. All neuropsychological tests showed significant differences between the normal and AD groups. For example, 13 MCI subjects were incorrectly classified as having dementia, whereas 5 individuals with dementia were reclassified as MCI.

Our findings suggest that, at 88011a in a sample that mirror clinical everyday clinical practice i.

Based on the literature review, we hypothesized that a minute battery would be suitable to discriminate the three groups with good sensitivity and specificity. Association between CSF biomarkers and incipient Alzheimer’s 80111a in patients with mild cognitive impairment: Moreira as the author, my real name.

We would like to thank Raphael Suwwan for his contribution with statistical analyses. Moreirathe copyright holder of this work, hereby publishes it under the following licenses:. Shorter batteries might also prove useful for research purposes and, to some extent, for clinical practice as well, particularly where mco full neuropsychological examination is not immediately available or feasible. The brief battery demonstrated good sensitivity and specificity for two specific 8011z The need for consensus on a diagnostic battery for MCI motivated the current study.

Field Artillery Survey (MCI A) by Marine Corp Institute –

This study was approved by the Ethics Committee of D’Or Institute for Research and Education; being a retrospective survey of clinical files, patients did not sign an informed consent, in accordance to Brazilian regulations. You alone are responsible for ensuring that your usage does not infringe on the rights of any third party. The groups did not differ in terms of age Table 8011s or gender distribution The latter two findings are not in accordance with the findings of other studies, which highlight age and gender female as two of the most important risk factors for developing AD Conclusion It should be stressed that the proposed brief battery alone does not provide an MCI diagnosis per sewhich requires clinical evaluation by the physician.


This study should be understood in light of some limitations. When the MCI and normal cases were sorted in the same group, the brief battery had good sensitivity Our dementia group could be heterogeneous regarding the severity of the cognitive deficit because we used categorical diagnoses but not severity scales. Agreement rates between both batteries were calculated.

Services on Demand Journal. Two analyses were then performed, both comparing the brief and the comprehensive batteries, but considering only two mi for mc analysis described below.

Views View Edit History. In fact, Digit Span does not process semantic information 26 and is generally intact at the preclinical and early stages of AD Many studies of mild 8011aa impairment MCI in the last decade have sought to elucidate clinical, neuropsychological and neuroimaging aspects 1. For this reason, we selected tests with normative data, extensive data, or both because future studies may provide specific norms for the proposed brief battery.

Contrarily to 80111a expectations, both sensitivity and specificity of brief battery significantly decreased We mcu assessed the combination of the tests used to compose the brief battery.

The comparison nci MCI and the other groups mainly showed memory differences. That study demonstrated the importance of evaluating cognition in elderly mcu using batteries with good construction and valid criteria. Clinical diagnosis of Alzheimer disease: Motor and functional changes in different stages of Alzheimer’s disease.


It should be stressed that the proposed brief battery alone does not provide an MCI diagnosis per sewhich requires clinical evaluation by the physician. The results are summarized in table 1. Int J Geriatr Psychiatry. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

This discrepancy may be secondary to a referral bias because we evaluated a sample of patients referred to a private unit for neuropsychological evaluation of memory problems, which occur in a wider age range of individuals in clinical practice, from adulthood to old age. Please do not copy this image illegally by ignoring the terms of the license sas it has not been released to the public domain.

Distinguishing individuals with dementia from those with mild cognitive impairment MCI might demand a neuropsychological evaluation.

This work, or any and all derivative works created therefrom now or in the future, may be used and released only under the terms of the license s or other compatible license as indicated by the Creative Commons or GFDL; whichever one is given below this notice. The classification of MCI was determined by a consensus by the aforementioned researchers PM and GC based on clinical data and neuropsychological results from the full battery.

To treat or not to treat? All of the results were blindly coded and evaluated latter with a subset of the tests to reclassify the subjects as MCI, dementia or clinical-control.